Collaboration Agreements Guide & Templates

This section aims to assist with managing agreements throughout the collaboration cycle, from initiation to completion. Navigate through to discover the “when, what and why” of each agreement and use the best practices and available example agreement template to tailor your contract according to your needs.

Note that this guide is for informational purposes only and is not legal advice. Please consult a legal professional before finalising agreements.

Contracts during a collaboration

A major challenge in research collaboration projects is their multidisciplinary nature, which requires partners with different goals, methods, and cultures to work together. Each partner may have unique interests, such as advancing research or commercializing products. For example, universities and research organizations aim to publish their findings, while businesses focus on gaining a competitive edge and growing. Publishing too early without protection can harm commercial interests and intellectual property, which is important for business partners.

Sharing and obtaining knowledge openly is key to driving innovation and collaboration. This openness is crucial because no one has a monopoly on invention. However, the emphasis on Open Innovation and Open Science in EU-funded projects brings challenges. Managing knowledge and protecting intellectual property becomes more complex in these multi-partner environments. Balancing individual and shared business strategies is essential for creating impactful and mutually beneficial innovation.

To ensure successful partnerships in research collaborations, a well-planned strategy using contracts and agreements can align and protect the interests of all partners. Here’s a suggested approach that stages agreements at critical points to guide partnerships toward their goals:


Collaboration Phase? When? What Agreements? Why?

Initiation

Start of collaboration discussions

  • Non-Disclosure Agreement (NDA)
  • Memorandum of Understanding (MoU)

  • NDA protects confidential information shared early.
  • MoU defines initial objectives and intentions for the partnership.

Planning

Once goals, roles, and resources are clear

  • Collaboration Agreement (CA)

  • CA formalises the nature of the partnership, specific roles, contributions, and IP management.

Execution

During active R&D, main project work, or technology scaling

  • Material Transfer Agreement (MTA), (if materials are transferred)
  • Facility Access (FA)/Visitors Agreement

  • MTA clarify resource sharing terms.
  • An FA can accelerate administrative tasks and confirm compliance with facility regulations

Commercialisation & Technology Transfer

At the project end or commercialization phase

  • Service Agreement (SA)
  • Licensing Agreement
  • Academic Spin-off agreement

  • SA defines quality expectations if RI services are involved
  • Licensing secures IP and commercialization rights.
  • A spin-off can further scale up the product or service and bridge it to the market.

Collaboration Phases

Initiation Phase: Setting the Collaboration Framework

The initiation phase marks the beginning of collaboration discussions, where potential partners start to explore the possibilities of working together. This phase focuses on setting the groundwork for the collaboration by establishing the basic terms, goals, and mutual expectations of all parties involved. At this stage, no detailed work or technology transfer is conducted, but rather, the partnership framework is outlined to ensure that all parties are aligned before entering into more formal agreements.

Key agreements in the Initiation phase typically include:

Non-Disclosure Agreement (NDA)

About

A non-disclosure agreement (NDA), or confidentiality agreement, is a legally binding contract where one party (the disclosing party) shares confidential information with another party (the receiving party), who agrees not to disclose it, or not to use it for any purposes other than those specified in the agreement. NDAs can be one-way, where only one party discloses information, or mutual, where both parties share confidential information.

It's advisable to enter into an NDA before negotiating license agreements or R&D projects and when discussing innovative ideas or technologies with potential partners. The best time to sign it is at the beginning of the outset of collaboration project negotiations, even before submitting a proposal.

Key Clauses:

Agreement template resources

In this section, you can find NDA templates that could be used for specific collaboration cases and tailored to the needs of each case.

Other relevant resources

Memorandum of Understanding (MoU)

About

A Memorandum of Understanding (MoU) is a formal document that outlines the terms and conditions of a partnership or collaboration between two or more parties. It serves as a framework for negotiations and cooperation, detailing the intentions, responsibilities, and expectations of the involved parties. While MoUs are typically non-binding, they provide a clear understanding of the shared goals and objectives of the collaboration and help delineate protocols for communication, information exchange, confidentiality, reporting, and the terms for modifying or terminating the agreement.

Best time to sign it is at the beginning of the outset of collaboration project negotiations, even before submitting a proposal.

Key Clauses:

Examples where an MoU could be useful:

An example of a MoU to build a network:

Agreement template resources

Planning Phase: Defining Roles and Responsibilities

The planning phase in a collaboration is crucial for ensuring that all parties involved in the collaboration understand their roles, contributions, and the overall objectives of the partnership. Once the goals, resources, and potential benefits are identified, the next step is to formalize these details in legally binding agreements.

Collaboration agreements, or collaborative research agreements, are established between two or more parties aiming to jointly develop and potentially commercialize new technologies or services. These agreements are legally binding and they outline each party’s contributions—resources, background IP, and expertise—while setting a legal framework for IP ownership, access rights, risk-sharing, and commercialisation terms.

A successful collaboration must be mutually beneficial, grounded in a win-win approach where all participants gain from the work involved. Therefore, it is essential to dedicate time and effort to carefully prepare the terms that need to be tailored to specific partnerships.

Below, we provide resources and templates to support the drafting of collaboration agreements across different collaboration models, as outlined in the Innovation Collaboration Models section, during the planning phase of a collaboration. Agreements relevant to the Commercialisation Pathways models, which may emerge from successful collaborations, can be found in the Commercialisation & Technology Transfer section.

Collaboration Model A1: Intra-RIs co-development

About

This is the case where academic institutions such as RIs, RPOs, or universities partner in collaborative research projects for technology or services development.

Agreement template resources

Collaboration model A2: Industry-RIs co-development

About

This is the case where academic institutions such as RIs, RPOs or universities can partner with Industry for technology or services co-development projects.

Agreement template resources

All models and a decision guide can be found here:

University and business collaboration agreements: model research collaboration agreements - GOV.UK

University and business collaboration agreements: decision guide - GOV.UK

Collaboration model A3: Mixed partners co-development

About

This is the case of a partnership between diverse partners such as RIs, industries, governmental bodies, or non-profit organizations that jointly work to develop new or existing technologies and services.


Agreement template resources

Collaboration model B1: Industry-Single RI development

Industry as a user: the downstream business model

About

In this model, industry approaches an RI with a specific problem or innovation need that requires the specialized expertise, resources, or facilities only the RI can provide.

This is the case where the collaboration could use the contact research approach, where a company will pay a full commercial fee for specified research to be performed using an RI/RPO facility, and the company expects to own all the intellectual property arising from the research. There are cases, however, where terms can allow right for academic research and or publications, or cases of a co-solution where a joint IP ownership is needed.

Agreement template resources

Find relevant model agreements following this collaboration approach as below:

Collaboration model B2: Single RI-Industry development

Industry as a supplier: the upstream business model

About

In this model, the RI initiates the collaboration, reaching out to an industry partner when it identifies a promising innovation need or technology that requires industry support to be scaled, validated or commercialized. This collaboration is often rooted in the RI’s expertise and preliminary R&D findings, where industry involvement is essential to increase TRL or deploy the technology at a commercial level.

Agreement template resources

Model agreement templates that could support the above approach to draft a collaboration agreement are below:

Execution Phase

The execution phase of a collaboration is where the research and development activities take place, and the focus shifts to achieving the goals set during the planning stage. It is also the phase where materials and resources are exchanged, and facilities are accessed to carry out collaborative research.

Key agreements during this phase are:

Material Transfer Agreement (MTA)

About

MTAs are used when exchanging tangible materials between parties to secure the IP rights of the material provider against possible disclosure by the recipient party. The material exchanged can take many forms, such as samples, chemical compounds, biological materials, prototypes, software, etc. It could also be patented materials transferred through a license.

Generally, such a transfer occurs during feasibility studies for compatibility matters, research activities on the material in R&D partnerships, provision of samples or prototypes to future clients for trials, etc.

Key elements:

Agreement template resources

Facility Access / Visitor Agreements

About

Facility access and visitor agreements are crucial during the development phase of a collaborative project, providing structured access to specialized labs or equipment. Agreements may be updated as project needs evolve or new personnel are added.

This type of agreement is specifically tailored for collaborative projects where facility access is integral to the research partnership but does not constitute a standalone service offering.

Key elements to consider:

Other relevant resources:

Commercialisation & Technology Transfer Phase

The technology transfer phase is the final stage in the collaboration journey, where the outcomes of the collaboration are translated into tangible products, services, or solutions that can be brought to the market. After a successful collaboration, many commercialization opportunities may arise. By translating research output into commercial applications, ENVRIs can not only enhance their research impact but also contribute to the development of innovative solutions that address industry needs, societal challenges, and market demands.

Below are three key commercialization pathways ENVRIs may explore after a successful collaboration:

  1. Service Provision
    ENVRIs can provide access to their advanced technologies, research facilities, and expertise to partners such as industry, government agencies, and other research organizations. This pathway involves offering services directly based on the research infrastructure's capabilities and expertise, such as:
    • Providing access to scientific data processing and analytics.
    • Offering access to specialized research facilities for product testing or prototyping.
    • Delivering knowledge transfer and consulting services to help partners apply research findings to real-world challenges.
  2. Licensing
    Licensing intellectual property (IP) allows ENVRIs to grant external partners the right to use developed technologies for commercial purposes. This pathway can involve licensing technologies, methodologies, or software created during the collaboration, enabling companies to integrate them into their products or services. Licensing agreements provide ENVRIs with revenue while enabling partners to bring these innovations to market.
  3. Spin-Offs
    When the research output has significant commercial potential, ENVRIs may establish spin-off companies. These independent companies focus on commercializing the technologies or other results developed within the collaboration. Spin-offs offer a dedicated vehicle for taking innovations to market and scaling them for wider application.

More details on the process, model agreements and templates to be used for each one of these commercialization pathways can be found in the Technology Transfer section of the Innovation Resources Toolbox.

Go to the Technology Transfer & Commercialisation section

References

Relevant Tool Reference

IPO UK-Lambert Toolkit

Intellectual Property Office. (2022, January 5). University and business collaboration agreements: Lambert Toolkit. GOV.UK. https://www.gov.uk/guidance/university-and-business-collaboration-agreements-lambert-toolkit

IPAG Unilateral Confidential Agreement

UNILATERAL CONFIDENTIALITY AGREEMENT. (n.d.). IPAG. Retrieved November 25, 2025, from https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Fexport%2Fsites%2Fwww%2Famc%2Fen%2Fdocs%2Fipagunilateralagrmnt.doc&wdOrigin=BROWSELINK

IPAG Multilateral Confidential Agreement

MULTILATERAL CONFIDENTIALITY AGREEMENT. (n.d.). IPAG. Retrieved November 25, 2025, from https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Fexport%2Fsites%2Fwww%2Famc%2Fen%2Fdocs%2Fipagmultinda.doc&wdOrigin=BROWSELINK

IPAG Short Confidential Agreement

DECLARATION OF CONFIDENTIALITY. (n.d.). IPAG. Retrieved November 25, 2025, from https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Fexport%2Fsites%2Fwww%2Famc%2Fen%2Fdocs%2Fipagshortnda.doc&wdOrigin=BROWSELINK

Mutual Non-Disclosure Agreement

European Innovation Council and SMEs Executive Agency. (2021, March 26). Mutual Non-Disclosure Agreement. European Commission. https://intellectual-property-helpdesk.ec.europa.eu/ip-management-and-resources/publications/mutual-non-disclosure-agreement_en

IPO Non-Disclosure Agreements

An Example of a Mutual Non-Disclosure Agreement. (n.d.). GOV.UK. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/592212/Example-Mutual-Non-Disclosure-Agreement.pdf

European IPR Helpdesk fact sheet

Fact Sheet—Non-Disclosure Agreement: A business tool. (2018, April). European IPR Helpdesk. https://intellectual-property-helpdesk.ec.europa.eu/document/download/4ed05406-4bca-46df-9696-951063368726_en?filename=Fact-Sheet-Non-Disclosure-Agreement.pdf

ENRIITC MoU

ENRIITC. (2022, November 30). MoU among RIs and ILOs to sustain the ENRIITC Network. https://ec.europa.eu/research/participants/documents/downloadPublic?documentIds=080166e5f4871f6b&appId=PPGMS

MoU before submitting a proposal

European Innovation Council and SMEs Executive Agency. (2021, March 26). H2020 MoU Memorandum of Understanding. European Commission. https://intellectual-property-helpdesk.ec.europa.eu/ip-management-and-resources/publications/h2020-mou-memorandum-understanding_en

WIPO model agreements and guide

Model Agreements. (2018, July 25). WIPO. https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Funiversities%2Fen%2Fdocs%2Fip_toolkit%2Fmodel_agreements.docx&wdOrigin=BROWSELINK

DESCA Model Consortium Agreement Guide

DESCA Model Consortium Agreement. (n.d.). Retrieved November 25, 2025, from https://www.desca-agreement.eu/desca-model-consortium-agreement/

WIPO model collaborative research agreement

Model Agreements. (2018, July 25). WIPO. https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Funiversities%2Fen%2Fdocs%2Fip_toolkit%2Fmodel_agreements.docx&wdOrigin=BROWSELINK

IPAG R&D cooperation model agreement

R+D COOPERATION AGREEMENT. (n.d.). IPAG. Retrieved November 25, 2025, from https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Fexport%2Fsites%2Fwww%2Famc%2Fen%2Fdocs%2Fipagrdcoop.doc&wdOrigin=BROWSELINK

University and business collaboration agreements: model research collaboration agreements

Intellectual Property Office. (2018, October 12). University and business collaboration agreements: Model research collaboration agreements. GOV.UK. https://www.gov.uk/government/publications/university-and-business-collaboration-agreements-model-research-collaboration-agreements

University and business collaboration agreements: decision guide

Intellectual Property Office. (2016, October 6). University and business collaboration agreements: Decision guide. GOV.UK. https://www.gov.uk/government/publications/university-and-business-collaboration-agreements-decision-guide

IPAG R&D cooperation master agreement

R+D COOPERATION MASTER AGREEMENT. (n.d.). IPAG. Retrieved November 25, 2025, from https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Fexport%2Fsites%2Fwww%2Famc%2Fen%2Fdocs%2Fipagmasteragrmt.doc&wdOrigin=BROWSELINK

Lambert consortium agreements

Intellectual Property Office. (2018, May 25). University and business collaboration agreements: Model consortium agreements. GOV.UK. https://www.gov.uk/government/publications/university-and-business-collaboration-agreements-model-consortium-agreements

WIPO contract research model agreement

Model Agreements. (2018, July 25). WIPO. https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Funiversities%2Fen%2Fdocs%2Fip_toolkit%2Fmodel_agreements.docx&wdOrigin=BROWSELINK

Lambert contract research model agreements

Intellectual Property Office. (2018, October 12). University and business collaboration agreements: Model research collaboration agreements. GOV.UK. https://www.gov.uk/government/publications/university-and-business-collaboration-agreements-model-research-collaboration-agreements

Lambert model agreement 4A

Intellectual Property Office. (2018, October 12). MODEL COLLABORATION AGREEMENT 4A. GOV.UK. https://assets.publishing.service.gov.uk/media/5b06861ded915d226a8d1b21/Collaboration_Agreement_4A__May_2018_.pdf

WIPO model material transfer agreements

Model Agreements. (2018, July 25). WIPO. https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Funiversities%2Fen%2Fdocs%2Fip_toolkit%2Fmodel_agreements.docx&wdOrigin=BROWSELINK

IPAG material transfer agreement

MATERIAL TRANSFER AGREEMENT. (n.d.). IPAG. Retrieved November 25, 2025, from https://view.officeapps.live.com/op/view.aspx?src=https%3A%2F%2Fwww.wipo.int%2Fexport%2Fsites%2Fwww%2Famc%2Fen%2Fdocs%2Fipagmta.doc&wdOrigin=BROWSELINK

European Charter for Access to Research Infrastructures-Principles and Guidelines for Access and Related Services

European Commission. Directorate General for Research and Innovation. (2016). European charter for access to research infrastructures: Principles and guidelines for access and related services. Publications Office. https://data.europa.eu/doi/10.2777/524573

Revised Charter for Access to Research Infrastructures to foster open science, innovation, and research security

European Commission. Directorate General for Research and Innovation. (2024). European Charter for Access to Research Infrastructures. https://op.europa.eu/en/publication-detail/-/publication/ec4692ae-ac6f-11ef-acb1-01aa75ed71a1/language-en